I-Vascular Embolization Device Polyvinyl Alcohol Embolic Microspheres

Izinkomba Zokusetshenziswa (Chaza)

I-Embolic Microsphereskuhloswe ukuthi kusetshenziselwe ukuhlanganisa i-arteriovenous malformations (AVMs) kanye nezimila ze-hypervascular, kuhlanganise ne-uterine fibroids.

Igama Elivamile noma Elivamile:I-Polyvinyl Alcohol Embolic MicrospheresUkwahlukanisa

Igama:Idivayisi Yokuqinisa I-Vascular

Ukuhlukaniswa: Ikilasi II

Iphaneli:Inhliziyo nemithambo yegazi

Incazelo Yedivayisi

Ama-Embolic Microspheres ama-microsphere e-hydrogel acindezelayo anomumo ojwayelekile, indawo ebushelelezi, nosayizi olinganisiwe, akhiwa ngenxa yokuguqulwa kwamakhemikhali ezintweni ze-polyvinyl alcohol (PVA).I-Embolic Microspheres iqukethe i-macromer ethathwe ku-polyvinyl alcohol (PVA), futhi ayi-hydrophilic, ayi-resorbable, futhi atholakala ngebanga losayizi.Isixazululo sokulondoloza yisisombululo se-sodium chloride esingu-0.9%.Okuqukethwe kwamanzi e-microsphere eyenziwe nge-polymerized ngokugcwele kungama-91% ~ 94%.Ama-Microspheres angakwazi ukubekezelela ukucindezelwa okungama-30%.

I-Embolic Microspheres inikezwa inyumba futhi ifakwe ezitsheni zengilazi ezivaliwe.

I-Embolic Microspheres ihloselwe ukuthi isetshenziselwe ukuhlanganisa i-arteriovenous malformations (AVMs) kanye nezimila ze-hypervascular, kuhlanganise ne-uterine fibroids.Ngokuvimbela ukunikezwa kwegazi endaweni okuhlosiwe, isimila noma ukukhubazeka kulambile ngenxa yezakhi zomzimba futhi ziyancipha ngosayizi.

I-Embolic Microspheres ingalethwa ngama-microcatheter ajwayelekile ebangeni elingu-1.7- 4 Fr.Ngesikhathi sokusetshenziswa, i-Embolic Microspheres ixubene ne-nonionic ejenti yokungafani ukuze yenze isisombululo sokumiswa.Ama-Embolic Microspheres ahloselwe ukusetshenziswa kanye futhi ahlinzekwa ayinyumba futhi angeyona i-pyrogenic.Ukulungiselelwa kwedivayisi ye-Embolic Microsphere kuchazwe kuThebula 1 nakuThebula 2 ngezansi.

Phakathi kobubanzi obuhlukahlukene bosayizi be-Embolic Microspheres, ububanzi besayizi obungasetshenziswa ekuhlanganiseni kwe-uterine fibroid yi-500-700μm, 700-900μm kanye no-900-1200μm.

Table: Ukucushwa kwedivayisi ye-Embolic Microspheres

Iincazelo

Proumgudu

Ikhodi

Ilinganisiwe

Usayizi (µm)

Qubuthi

HyIzimila ze-pervascular/ Arteriovenous

Malformations

I-Uterine Fibroid

B107S103 100-300

I-1ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Cha

B107S305 300-500

I-1ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Cha

B107S507 500-700

I-1ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo

B107S709 700-900

I-1ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo

B107S912 900-1200

I-1ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo

I-B207S103 100-300

I-2ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Cha

B207S305 300-500

I-2ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Cha

B207S507 500-700

I-2ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo

B207S709 700-900

I-2ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo

I-B207S912 900-1200

I-2ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo