I-Vascular Embolization Device Polyvinyl Alcohol Embolic Microspheres

Izinkomba Zokusetshenziswa (Chaza)

I-Embolic Microsphereskuhloswe ukuthi kusetshenziselwe ukuhlanganisa i-arteriovenous malformations (AVMs) kanye nezimila ze-hypervascular, kuhlanganise ne-uterine fibroids.

Igama Elivamile noma Elivamile:I-Polyvinyl Alcohol Embolic MicrospheresUkwahlukanisa

Igama:Idivayisi Yokuqinisa Imithambo yegazi

Ukuhlukaniswa: Ikilasi II

Iphaneli:Inhliziyo nemithambo yegazi

Incazelo Yedivayisi

I-Embolic Microspheresama-microspheres e-hydrogel acindezelayo anomumo ojwayelekile, indawo ebushelelezi, nosayizi olinganisiwe, akhiwa ngenxa yokuguqulwa kwamakhemikhali ezintweni ze-polyvinyl alcohol (PVA). I-Embolic Microspheres iqukethe i-macromer ethathwe ku-polyvinyl alcohol (PVA), futhi ayi-hydrophilic, ayi-resorbable, futhi atholakala ngebanga losayizi. Isixazululo sokulondoloza yisisombululo se-sodium chloride esingu-0.9%. Okuqukethwe kwamanzi e-microsphere eyenziwe nge-polymerized ngokugcwele kungama-91% ~ 94%. Ama-Microsphere angakwazi ukubekezelela ukucindezelwa okungama-30%.

I-Embolic Microspheres inikezwa inyumba futhi ifakwe ezitsheni zengilazi ezivaliwe.

I-Embolic Microspheres ihloselwe ukusetshenziselwa ukuhlanganisa i-arteriovenous malformations (AVMs) kanye nezimila ze-hypervascular, kuhlanganise ne-uterine fibroids. Ngokuvimbela ukunikezwa kwegazi endaweni okuhlosiwe, isimila noma ukukhubazeka kulambile ngenxa yezakhi zomzimba futhi ziyancipha ngosayizi.

I-Embolic Microspheres ingalethwa ngama-microcatheter ajwayelekile ebangeni elingu-1.7- 4 Fr. Ngesikhathi sokusetshenziswa, i-Embolic Microspheres ixubene ne-nonionic ejenti yokungafani ukuze yenze isisombululo sokumiswa. Ama-Embolic Microspheres ahloselwe ukusetshenziswa kanye futhi ahlinzekwa ayinyumba futhi angeyona i-pyrogenic. Ukulungiselelwa kwedivayisi ye-Embolic Microsphere kuchazwe kuThebula 1 nakuThebula 2 ngezansi.

Phakathi kobubanzi obuhlukahlukene bosayizi be-Embolic Microspheres, ububanzi besayizi obungasetshenziswa ekuhlanganisweni kwe-uterine fibroid yi-500-700μm, 700-900μm kanye no-900-1200μm.

Table: Ukucushwa kwedivayisi ye-Embolic Microspheres

Iincazelo

Proumgudu

Ikhodi

Ilinganisiwe

Usayizi (µm)

Qubuthi

HyIzimila ze-pervascular/ Arteriovenous

Malformations

I-Uterine Fibroid

B107S103 100-300

I-1ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Cha

B107S305 300-500

I-1ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Cha

B107S507 500-700

I-1ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo

B107S709 700-900

I-1ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo

B107S912 900-1200

I-1ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo

I-B207S103 100-300

I-2ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Cha

B207S305 300-500

I-2ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Cha

B207S507 500-700

I-2ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo

B207S709 700-900

I-2ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo

I-B207S912 900-1200

I-2ml microspheres: 7ml 0.9%

i-sodium chloride

Yebo Yebo