Muva nje, abezindaba baphesheya kwezilwandle iFierce Medtech ikhethe iziteshi eziyi-15 ezintsha kakhuluizinkampani zamadivayisi ezokwelaphango-2023. Lezi zinkampani azigcini nje ngokugxila emikhakheni yezobuchwepheshe evame kakhulu, kodwa futhi zisebenzisa umqondo wazo obukhali ukuthola izidingo zezokwelapha ezingaba khona.
01
Ukuhlinzwa kwe-Activ
Nikeza odokotela abahlinzayo ulwazi olubonakalayo lwesikhathi sangempela
I-CEO: uManisha Shah-Bugaj
Yasungulwa: 2017
Kutholakala e: Boston
I-Activ Surgical iqede ukuhlinzwa kwerobhothi kokuqala okuzenzakalelayo emhlabeni kwezicubu ezithambile. Le nkampani ithole imvume ye-FDA ngomkhiqizo wayo wokuqala, i-ActivSight, imodyuli yokuhlinzwa evuselela idatha yezithombe ngokushesha.
I-ActivSight isetshenziswa izikhungo ezingaba yishumi nambili e-United States ekuhlinzeni i-colorectal, thoracic kanye ne-bariatric, kanye nezinqubo ezijwayelekile njengokususwa kwe-gallbladder. Ama-prostatectomies amaningi e-robotic nawo enziwe kusetshenziswa i-ActivSight.
02
Ama-Bionics e-Beta
Ama-pancreas Okwenziwa Aguquguqukayo
I-CEO: uSean Saint
Yasungulwa: 2015
Indawo: Irvine, eCalifornia
Izinhlelo zokulethwa kwe-insulin ezizenzakalelayo zithandwa kakhulu emhlabeni wezobuchwepheshe besifo sikashukela. Uhlelo, olwaziwa ngokuthi uhlelo lwe-AID, lwakhiwe nge-algorithm ethatha ukufundwa kwe-glucose egazini kusuka ku-glucose monitor eqhubekayo, kanye nolwazi mayelana nokudla kwama-carbohydrate nomsebenzi womuntu, futhi lubikezela lawo mazinga emizuzu embalwa ezayo. Izinguquko ezingase zenzeke ngaphakathi kwephampu ye-insulin ngaphambi kokulungisa umphumela wephampu ye-insulin ukuze kugwenywe i-hyperglycemia noma i-hypoglycemia ebikezelwayo.
Le ndlela yobuchwepheshe obuphezulu idala lokho okubizwa ngokuthi uhlelo oluvaliwe oluhlanganisiwe, noma ama-pancreas okwenziwa, olwenzelwe ukunciphisa umsebenzi wokusebenza ngezandla kwabanesifo sikashukela.
I-Beta Bionics ithatha lo mgomo isinyathelo esisodwa phambili ngobuchwepheshe bayo be-iLet bionic pancreas. Uhlelo lwe-iLet ludinga kuphela ukuthi kufakwe isisindo somsebenzisi, okususa isidingo sokubala okukhathazayo kokudla ama-carbohydrate.
03
Impilo yaseCala
Ukwelashwa okuwukuphela komhlaba okugqokwayo kokuthuthumela
Osihlalo Ababambisene: Kate Rosenbluth, Ph.D., Deanna Harshbarger
Yasungulwa: 2014
Kutholakala e: San Mateo, eCalifornia
Iziguli ezine-essential tremble (ET) sezinesikhathi eside zintula ukwelashwa okusebenzayo nokunengozi encane. Iziguli zingenza ukuhlinzwa kobuchopho okuhlaselayo kuphela ukuze kufakwe idivayisi yokuvuselela ubuchopho ejulile, ngokuvamile enemiphumela emincane kuphela, noma imithi elinganiselwe elapha izimpawu kuphela kodwa hhayi imbangela eyinhloko, futhi engabangela imiphumela emibi kakhulu.
Inkampani entsha yeSilicon Valley iCala Health isungule idivayisi egqokwayo yokuthuthumela okubalulekile enganikeza ukwelashwa kokushintshashintsha kwemizwa ngaphandle kokuphula isikhumba.
Idivayisi yenkampani iCala ONE yavunywa okokuqala yi-FDA ngo-2018 ukuze isetshenziswe kuphela ekwelapheni ukuthuthumela okubalulekile. Ehlobo eledlule, iCala ONE yethule uhlelo lwayo lwesizukulwane esilandelayo nge-510(k) clearance: iCala kIQ™, idivayisi yokuqala neyodwa evunyelwe yi-FDA enikeza ukwelashwa kwezandla okusebenzayo kweziguli ezine-essential tremb kanye nesifo sikaParkinson. Idivayisi egqokwayo yokwelapha ukuthuthumela okubalulekile.
04
I-Causaly
Ukuguqula Usesho Lwezokwelapha
I-CEO: uYiannis Kiachopoulos
Yasungulwa: 2018
Kutholakala e: eLondon
I-Causaly isungule lokho uKiachopoulos akubiza ngokuthi “umshayeli we-AI okhiqiza izinga lokuqala lokukhiqiza” ovumela ososayensi ukusheshisa ukusesha ulwazi. Amathuluzi e-AI azophenya lonke ucwaningo lwezokwelapha olushicilelwe futhi anikeze izimpendulo eziphelele zemibuzo eyinkimbinkimbi. Lokhu kusiza izinkampani ezithuthukisa imithi ukuthi zibe nokuzethemba okwengeziwe ezinqumweni ezizenzayo, njengoba amakhasimende azi ukuthi ithuluzi lizonikeza ulwazi oluphelele mayelana nendawo yesifo noma ubuchwepheshe.
Into eyingqayizivele ngeCausaly ukuthi noma ubani angayisebenzisa, ngisho nabantu abavamile.
Okuhle kunakho konke, abasebenzisi akudingeki bazifundele yonke imibhalo ngokwabo.
Enye inzuzo yokusebenzisa i-Causaly ukuhlonza imiphumela emibi engaba khona ukuze izinkampani zikwazi ukususa izinhloso.
05
Isayensi Yezinto Eziphilayo
Inselele unxantathu ongenakwenzeka wekhwalithi, izindleko kanye nokusebenza kahle
I-CEO: Molly He
Yasungulwa: 2017
Kutholakala e: San Diego
Uhlelo lwenkampani i-Aviti luzoqala ukusebenza ekuqaleni kuka-2022. Njengedivayisi elingana nedeskithophu, iqukethe amaseli amabili okugeleza angasebenza ngokuzimela, okunciphisa kakhulu izindleko zokulandelana. I-Aviti24, okulindeleke ukuthi iqale ukusebenza engxenyeni yesibili yalo nyaka, yenzelwe ukuhlinzeka ngokuthuthukiswa kwemishini efakiwe njengamanje futhi iwaguqule abe amasethi e-hardware angakwazi ukuhlaziya hhayi i-DNA ne-RNA kuphela, kodwa futhi namaprotheni kanye nokulawulwa kwawo, kanye nokwakheka kwamaseli.
06
Nika amandla ukujova
Ukuphathwa nge-intravenous noma nini, noma kuphi
I-CEO: uMike Hooven
Yasungulwa: 2010
Kutholakala eCincinnati
Njengenkampani yezobuchwepheshe bezokwelapha esineminyaka engaphezu kweshumi isungulwa, i-Enable Injections yenza intuthuko muva nje.
Kuleli hlobo, inkampani ithole idivayisi yayo yokuqala evunyelwe yi-FDA, idivayisi ejovayo ye-EMPAVELI, egcwele i-Pegcetacoplan, ukwelashwa kokuqala okuqondiswe ku-C3 ukwelapha i-PNH (i-paroxysmal nocturnal hemoglobinuria). I-Pegcetacoplan iyindlela yokuqala yokwelapha evunyelwe yi-FDA ngo-2021. Ukwelashwa okuqondiswe ku-C3 kokwelapha i-PNH nakho kuyisidakamizwa sokuqala emhlabeni esivunyelwe ukwelapha i-macular geographic atrophy.
Ukuvunyelwa lokhu kuwumphumela weminyaka eminingi yomsebenzi wenkampani kumadivayisi okulethwa kwezidakamizwa aklanyelwe ukuba abe nobungane nesiguli ngenkathi evumela ukuphathwa kwemithamo emikhulu ngemithambo yegazi.
07
I-Exo
Inkathi entsha ye-ultrasound ephathwa ngesandla
I-CEO: u-andeep Akkaraju
Yasungulwa: 2015
Kutholakala e: Santa Clara, eCalifornia
I-Exo Iris, idivayisi ye-ultrasound ephathwa ngesandla eyasungulwa yi-Exo ngoSepthemba 2023, yabizwa ngokuthi “inkathi entsha ye-ultrasound” ngaleso sikhathi, futhi yaqhathaniswa nemishini yokucwaninga ephathwa ngesandla evela ezinkampanini ezifana ne-GE Healthcare kanye ne-Butterfly Network.
I-probe ephathwa ngesandla ye-Iris ithwebula izithombe ngensimu yokubuka engama-degree angu-150, ethi inkampani ingamboza isibindi sonke noma umbungu wonke kuze kube ngamasentimitha angu-30. Ungashintsha futhi phakathi kwe-curved, linear noma phased array, kanti izinhlelo ze-ultrasound zendabuko zivame ukudinga ama-probe ahlukene.
08
Ukwelapha kweGenesis
Inkanyezi Ekhulayo Yezemithi ye-AI
I-CEO: u-Evan Feinberg
Yasungulwa: 2019
Kutholakala e: Palo Alto, eCalifornia
Ukufaka ukufunda komshini kanye nobuhlakani bokwenziwa ekuthuthukisweni kwezidakamizwa kuyindawo enkulu yokutshalwa kwezimali embonini yezokwelapha ngemithi.
I-Genesis ihlose ukwenza lokhu ngeplatifomu yayo ye-GEMS, isebenzisa uhlelo olusha olwakhiwe ngabasunguli benkampani ukuklama ama-molecule amancane, kunokuthembela ezinhlelweni zokuklama ezingezona ezamakhemikhali ezikhona.
Ipulatifomu ye-Genesis Therapeutics' GEMS (Genesis Exploration of Molecular Space) ihlanganisa amamodeli okubikezela asekelwe ekufundeni okujulile, ukulingisa kwama-molecule kanye namamodeli olimi lokuqonda amakhemikhali, ngethemba lokudala izidakamizwa ezincane zama-molecule "ezihamba phambili" ezinamandla aphezulu kakhulu nokukhetha. , ikakhulukazi ekuqondiseni izinhloso ezazingatholakali ngaphambili.
09
Ukugeleza Kwenhliziyo
Umholi we-FFR
I-CEO: UJohn Farquhar
Yasungulwa: 2010
Kutholakala e: Mountain View, eCalifornia
I-HeartFlow ingumholi ku-Fractional Flow Reserve (FFR), uhlelo oluhlola ama-3D CT angiography scans enhliziyo ukuze kutholakale i-plaque kanye nokuvinjelwa emithanjeni yenhliziyo.
Ngokunikeza umbono wokugeleza kwegazi elinomoya-mpilo emisipheni yenhliziyo kanye nokulinganisa ngokusobala izindawo zemithambo yegazi evalekile, inkampani isungule indlela eyenzelwe wena yokungenelela ezimweni ezifihliwe ezibangela amashumi ezigidi zezinhlungu zesifuba kanye nokuhlaselwa yinhliziyo minyaka yonke. Izizathu ezibangela amacala okuxhuzula.
Umgomo wethu omkhulu ukwenza ngezifo zenhliziyo nalokho esikwenzayo ngomdlavuza ngokuhlolwa kwangaphambi kwesikhathi kanye nokwelashwa komuntu siqu, kusiza odokotela ukuba benze izinqumo ezinolwazi ngokusekelwe ezidingweni zesiguli ngasinye.
10
Karius
Yilwa nezifo ezingaziwa
I-CEO: u-Alec Ford
Yasungulwa: 2014
Kutholakala e: Redwood City, eCalifornia
Ukuhlolwa kwe-Karius ubuchwepheshe obusha bokuxilonga ngoketshezi obungakwazi ukubona amagciwane angaphezu kwe-1,000 athelelekayo ekukhishweni kwegazi okukodwa emahoreni angama-26. Ukuhlolwa kungasiza odokotela ukuba bagweme ukuxilongwa okuningi okuhlaselayo, kunciphise izikhathi zokuphendula, futhi kugweme ukubambezeleka ekwelapheni iziguli ezibhedlela.
11
I-Linus Biotechnology
Izinwele eziyi-1cm zokuxilonga i-autism
I-CEO: UDkt. Manish Arora
Yasungulwa: 2021
Kutholakala eNorth Brunswick, eNew Jersey
I-StrandDx ingasheshisa inqubo yokuhlola ngekhithi yokuhlola ekhaya edinga ukuthi kuthunyelwe umucu wezinwele enkampanini ukuze kutholakale ukuthi i-autism ingasuswa yini.
12
I-Namida Lab
Isivikelo sezinyembezi somdlavuza webele
I-CEO: Omid Moghadam
Yasungulwa: 2019
Kutholakala eFayetteville, e-Arkansas
I-Auria iyisivivinyo sokuqala sokuhlolwa komdlavuza webele ekhaya esisekelwe ekudabukeni okungeyona indlela yokuxilonga ngoba ayinikezi umphumela wesibili oshoyo ukuthi umdlavuza webele ukhona yini. Esikhundleni salokho, ihlanganisa imiphumela ibe yizigaba ezintathu ngokusekelwe emazingeni ama-biomarker amabili ephrotheni futhi incoma ukuthi umuntu kufanele yini afune ukuqinisekiswa okwengeziwe ku-mammogram ngokushesha okukhulu.
13
I-Noah Medical
i-biopsy yamaphaphu entsha
Isikhulu esiphezulu: Zhang Jian
Yasungulwa: 2018
Kutholakala e: San Carlos, eCalifornia
I-Noah Medical iqoqe amaRandi ayizigidi ezingu-150 ngonyaka odlule ukusiza uhlelo lwayo lwe-bronchoscopy oluqondiswa yi-Galaxy ukuthi luncintisane nezikhondlakhondla ezimbili embonini, ipulatifomu ye-Ion ye-Intuitive Surgical kanye ne-Monarch kaJohnson & Johnson.
Zonke lezi zinsimbi ezintathu zenzelwe ukuba yi-probe encane efaka i-bronchi kanye nemigudu yamaphaphu ngaphandle, okusiza odokotela abahlinzayo ukuthi bafune izilonda kanye namaqhubu okusolwa ukuthi afihla izimila ezinomdlavuza. Kodwa-ke, uNoah, njengomuntu ofike sekwephuzile, wathola imvume ye-FDA ngoMashi 2023.
NgoJanuwari kulo nyaka, uhlelo lwenkampani iGalaxy luqede ukuhlolwa kwalo kwama-500.
Into enhle ngoNoah ukuthi uhlelo lusebenzisa izingxenye ezingasetshenziswa kabusha ngokuphelele, futhi yonke ingxenye ethinta isiguli ingalahlwa futhi ithathelwe indawo yi-hardware entsha.
14
I-Procyrion
Ukwelapha izifo zenhliziyo nezinso ngendlela exakile
Isikhulu Esiphezulu: u-Eric Fain, MD
Yasungulwa: 2005
Kutholakala e: Houston
Kwabanye abantu abanesifo senhliziyo, kwenzeka i-feedback loop ebizwa ngokuthi i-cardiorenal syndrome, lapho imisipha yenhliziyo ebuthakathaka iqala ukwehla emandleni ayo okukhipha uketshezi emzimbeni lapho imisipha yenhliziyo ebuthakathaka ingakwazi ukuthwala igazi nomoya-mpilo ezinso. Lokhu kuqongelela koketshezi, nakho kwandisa isisindo sokushaya kwenhliziyo.
I-Procyrion ihlose ukuphazamisa lokhu kusabela ngephampu ye-Aortix, ithuluzi elincane, elisekelwe ku-catheter elingena e-aorta yomzimba ngesikhumba futhi lehle liye esifubeni nasesiswini.
Isebenza ngokufana nezinye izimpompi zenhliziyo ezisekelwe ku-impeller, ukuyibeka phakathi komunye wemithambo emikhulu yomzimba ngesikhathi esisodwa kunciphisa umthwalo womsebenzi enhliziyweni engenhla futhi kusiza ukugeleza kwegazi okuya ezinso.
15
I-Proprio
Dala imephu yokuhlinzwa
I-CEO: uGabriel Jones
Yasungulwa: 2016
Kutholakala e: Seattle
I-Paradigm, inkampani ye-Proprio, iyipulatifomu yokuqala yokusebenzisa ubuchwepheshe bensimu yokukhanya kanye nobuhlakani bokwenziwa ukukhiqiza izithombe ze-3D zesikhathi sangempela zesimo somzimba wesiguli ngesikhathi sokuhlinzwa ukusekela ukuhlinzwa komgogodla.
Isikhathi sokuthunyelwe: Mashi-28-2024