Muva nje, abezindaba baphesheya kwezilwandle i-Fierce Medtech ikhethe i-15 entsha kakhuluizinkampani zemishini yezokwelaphango-2023. Lezi zinkampani azigxili kuphela emikhakheni yezobuchwepheshe evamile, kodwa futhi zisebenzisa ingqondo yazo ebukhali ukuze zithole izidingo zezokwelapha ezingaba khona.
01
Ukuhlinzwa Okusebenzayo
Nikeza odokotela abahlinzayo ngemininingwane ebonakalayo yesikhathi sangempela
CEO: Manisha Shah-Bugaj
Isungulwe: 2017
Indawo: Boston
I-Active Surgical iqedele ukuhlinzwa kwerobhothi okuzenzakalelayo kokuqala emhlabeni kwezicubu ezithambile. Inkampani ithole imvume ye-FDA ngomkhiqizo wayo wokuqala, i-ActiveSight, imojula yokuhlinza elungisa ngokushesha idatha yokuthwebula.
I-ActiveSight isetshenziswa cishe izikhungo eziyishumi nambili e-United States ngokuhlinzwa kwe-colorectal, thoracic kanye ne-bariatric, kanye nezinqubo ezijwayelekile ezifana nokususwa kwenyongo. Amarobhothi amaningi e-prostatectomies nawo ayenziwe kusetshenziswa i-ActiveSight.
02
I-Beta Bionics
I-Revolutionary Pancreas Artificial
Isikhulu esiphezulu: Sean Saint
Isungulwe: 2015
Indawo: Irvine, California
Izinhlelo ezizenzakalelayo zokulethwa kwe-insulin yizo zonke ezicasulayo emhlabeni wezobuchwepheshe besifo sikashukela. Uhlelo, olwaziwa ngokuthi uhlelo lwe-AID, lwakhiwe ngokuzungeza i-algorithm ethatha ukufundwa kweglucose yegazi kusiqapha esiqhubekayo se-glucose, kanye nolwazi lokudla kwama-carbohydrate omsebenzisi namazinga omsebenzi, futhi ibikezela lawo mazinga emaminithini ambalwa alandelayo. izinguquko ezingase zenzeke ngaphakathi kwephampu ye-insulin ngaphambi kokulungiswa kwephampu ye-insulin ukuze kugwenywe i-hyperglycemia engabikezelwa noma i-hypoglycemia.
Le ndlela yobuchwepheshe obuphezulu idala lokho okubizwa ngokuthi i-hybrid clover-loop system, noma amanyikwe okwenziwa, aklanyelwe ukunciphisa ukusebenza ngezandla kwabanesifo sikashukela.
I-Beta Bionics ithatha le nhloso isinyathelo esisodwa ukuya phambili ngobuchwepheshe bayo be-iLet bionic pancreas. Uhlelo lwe-iLet ludinga kuphela ukuthi kufakwe isisindo somsebenzisi, okuqeda isidingo sokubala okunzima kokudla ama-carbohydrate.
03
I-Cala Health
Ukwelapha okugqokwayo emhlabeni kuphela kokundindizela
Co-Chairs: Kate Rosenbluth, Ph.D., Deanna Harshbarger
Isungulwe: 2014
Indawo: San Mateo, California
Iziguli ezinokuthuthumela okubalulekile (ET) kudala zintula ukwelashwa okusebenzayo, okunobungozi obuncane. Iziguli zingahlinzwa kuphela ebuchosheni ukuze zifake idivayisi ejulile yokuvuselela ubuchopho, ngokuvamile enemiphumela engemihle, noma imithi elinganiselwe elapha izimpawu kuphela kodwa hhayi imbangela eyinhloko, futhi ingase ibangele imiphumela emibi kakhulu.
Isiqalo se-Silicon Valley i-Cala Health yenze idivayisi egqokekayo yokundindizela okubalulekile engaletha ukwelashwa kwe-neuromodulation ngaphandle kokuphuka kwesikhumba.
Idivayisi yenkampani ye-Cala ONE yagunyazwa okokuqala yi-FDA ngo-2018 ukuze zelashwe kuphela ukuzamazama okubalulekile. Ehlobo eledlule, i-Cala ONE yethule uhlelo lwayo lwesizukulwane esilandelayo olunemvume engu-510(k): I-Cala kIQ™, idivayisi yokuqala newukuphela kwayo egunyazwe i-FDA ephathwa ngesandla ehlinzeka ngokwelashwa okusebenzayo kwezandla ezigulini ezinokundindizela okubalulekile nesifo sika-Parkinson. Idivayisi egqokekayo yokwelapha ukuthuthumela.
04
Isizathu
I-Revolutionizing Medical Search
CEO: Yiannis Kiachopoulos
Isungulwe: 2018
Indawo: London
I-Causaly ithuthukise lokho i-Kiachopoulos ekubiza ngokuthi "umshayeli we-AI okhiqizayo wezinga lokuqala lezinga lokukhiqiza" okwenza ososayensi bakwazi ukusheshisa ukusesha ulwazi. Amathuluzi e-AI azophenya lonke ucwaningo lwe-biomedical eshicilelwe futhi anikeze izimpendulo eziphelele emibuzweni eyinkimbinkimbi. Lokhu kusiza izinkampani ezakha izidakamizwa zibe nokuzethemba okwengeziwe ezinqumweni ezizenzayo, njengoba amakhasimende azi ukuthi ithuluzi lizonikeza ulwazi olugcwele mayelana nendawo yesifo noma ubuchwepheshe.
Into eyingqayizivele nge-Causaly ukuthi noma ubani angayisebenzisa, ngisho nama-laymen.
Okuhle kunakho konke, abasebenzisi akudingeki bazifundele wonke amadokhumenti ngokwabo.
Enye inzuzo yokusebenzisa i-Causaly ukuhlonza imiphumela emibi engaba khona ukuze izinkampani zikwazi ukuqeda okuhlosiwe.
05
I-Element Biosciences
Inselele unxantathu ongenakwenzeka wekhwalithi, izindleko nokusebenza kahle
CEO: Molly He
Isungulwe: 2017
Indawo: San Diego
Uhlelo lwenkampani lwe-Aviti luzoqala ekuqaleni kuka-2022. Njengedivayisi yedeskithophu, iqukethe amaseli amabili okugeleza angasebenza ngokuzimela, anciphise kakhulu izindleko zokulandelana. I-Aviti24, okulindeleke ukuthi iqale ukuvela engxenyeni yesibili yalo nyaka, iklanyelwe ukuhlinzeka ngezithuthukisi emishinini efakiwe njengamanje futhi iguqule ibe amasethi e-hardware ekwazi ukuhlukanisa hhayi i-DNA ne-RNA kuphela, kodwa namaprotheni nokulawulwa kwawo, kanye ne-cell morphology. .
06
Nika amandla Imijovo
Ukulawulwa ngomjovo noma nini, noma kuphi
Isikhulu esiphezulu: UMike Hooven
Yasungulwa: 2010
Kutholakala e: Cincinnati
Njengenkampani yobuchwepheshe bezokwelapha eminyakeni engaphezu kweshumi kwenziwa, i-Vumela Imijovo ithatha izinyathelo muva nje.
Lokhu kuwa, inkampani ithole idivayisi yayo yokuqala egunyazwe yi-FDA, i-EMPAVELI injectable device, elayishwe nge-Pegcetacoplan, ukwelapha okuhlosiwe kwe-C3 yokuqala yokwelapha i-PNH (i-paroxysmal nocturnal hemoglobinuria). I-Pegcetacoplan iwukwelashwa kokuqala okugunyazwe yi-FDA ngo-2021. Ukwelashwa okuhlosiwe kwe-C3 kokwelashwa kwe-PNH futhi kuwumuthi wokuqala emhlabeni ogunyazwe ukwelapha i-macular geographic atrophy.
Ukugunyazwa umvuthwandaba weminyaka yokusebenza kwenkampani emishinini yokulethwa kwezidakamizwa edizayinelwe ukuthi ibe nobungane nesineke kuyilapho ivumela ukulawulwa ngomthambo imithamo emikhulu.
07
Exo
Inkathi entsha ye-ultrasound ephathwayo
CEO: andeep Akkaraju
Isungulwe: 2015
Indawo: Santa Clara, California
I-Exo Iris, idivayisi ye-ultrasound ephathwa ngesandla eyethulwe i-Exo ngoSepthemba 2023, yadunyiswa “njengenkathi entsha ye-ultrasound” ngaleso sikhathi, futhi yaqhathaniswa nophenyo oluphathwa ngesandla oluvela ezinkampanini ezifana ne-GE Healthcare kanye ne-Butterfly Network.
Uphenyo oluphathwa ngesandla lwe-Iris luthwebula izithombe ezinomkhakha wokubuka ongu-150-degree, inkampani ethi ingamboza sonke isibindi noma umbungu wonke ekujuleni okungamasentimitha angama-30. Ungakwazi futhi ukushintsha phakathi kwamalungu afanayo agobile, aqondile noma ahlukaniswe ngezigaba, kuyilapho amasistimu e-ultrasound endabuko ngokuvamile edinga ama-probe ahlukene.
08
Genesis Therapeutics
I-AI Pharmaceutical Rising Star
Isikhulu esiphezulu: Evan Feinberg
Isungulwe: 2019
Indawo: Palo Alto, California
Ukufaka ukufunda ngomshini kanye nobuhlakani bokwenziwa ekuthuthukisweni kwezidakamizwa indawo enkulu yokutshala imali embonini ye-biopharmaceutical.
IGenesis ihlose ukwenza lokhu ngenkundla yayo yakwa-GEMS, isebenzisa uhlelo olusha olwakhiwe abasunguli benkampani ukuklama ama-molecule amancane, kunokuthembela ezinhlelweni ezikhona zokuklama okungewona amakhemikhali.
Inkundla ye-GEMS ye-Genesis Therapeutics (Genesis Exploration of Molecular Space) ihlanganisa amamodeli okuqagela asekelwe ekufundeni ajulile, ukulingisa kwamangqamuzana namamodeli olimi okuqonda amakhemikhali, ngethemba lokudala izidakamizwa ze-molecule ezincane “ezisezingeni lokuqala” ezinamandla amakhulu nokukhetha. , ikakhulukazi ukukhomba okuhlosiwe okwakungalawuleki ngaphambilini.
09
Ukugeleza Kwenhliziyo
Umholi we-FFR
CEO: John Farquhar
Yasungulwa: 2010
Indawo: Mountain View, California
I-HeartFlow ingumholi ku-Fractional Flow Reserve (FFR), uhlelo oluhlinza izikena ze-3D CT angiography zenhliziyo ukuze zihlonze uqwembe nokuvaleka kwemithambo yenhliziyo.
Ngokuhlinzeka ngeso lengqondo ukugeleza kwegazi elifakwe umoya-mpilo emcupheni wenhliziyo kanye nokulinganisa ngokucacile izindawo zemithambo yegazi eboshiwe, inkampani isungule indlela yomuntu siqu yokungenelela ezimweni ezifihliwe ezibangela amashumi ezigidi zezinhlungu zesifuba kanye nokuhlaselwa yinhliziyo njalo ngonyaka Izizathu ngemuva. amacala okuthumba.
Umgomo wethu omkhulu uwukwenza esifweni senhliziyo nemithambo yegazi lokho esikwenzela umdlavuza ngokuhlola kusenesikhathi nokwelashwa komuntu siqu, ukusiza odokotela benze izinqumo ezinolwazi ngokusekelwe ezidingweni zesiguli ngasinye.
10
Karius
Yilwa nezifo ezingaziwa
Isikhulu esiphezulu: Alec Ford
Isungulwe: 2014
Indawo: Redwood City, California
Ukuhlolwa kwe-Karius kuyinoveli yobuchwepheshe be-biopsy obuwuketshezi obukwazi ukubona izifo ezithathelwanayo ezingaphezu kwe-1,000 ngokudonsa igazi elilodwa emahoreni angama-26. Ukuhlolwa kungasiza odokotela bagweme ukuxilonga okuningi okuhlaselayo, banciphise izikhathi zokushintsha, futhi bagweme ukubambezeleka ekwelapheni iziguli ezilaliswe esibhedlela.
11
I-Linus Biotechnology
Izinwele ezi-1cm zokuxilonga i-autism
Isikhulu esiphezulu: UDkt. Manish Arora
Isungulwe: 2021
Indawo: North Brunswick, New Jersey
I-StrandDx ingasheshisa inqubo yokuhlola ngekhithi yokuhlola ekhaya edinga ukuthi umucu wezinwele nje ubuyiselwe enkampanini ukuze kunqunywe ukuthi i-autism ingakhishwa.
12
Namida Lab
Izinyembezi zihlola umdlavuza webele
Isikhulu esiphezulu: Omid Moghadam
Isungulwe: 2019
Indawo: Fayetteville, Arkansas
I-Auria iwukuhlolwa kokuqala okusekelwe ezinyembezini ekhaya okungeyona indlela yokuxilonga ngoba ayinikezi ngomphumela kanambambili osho ukuthi ukhona yini umdlavuza webele. Kunalokho, ihlanganisa imiphumela ibe izigaba ezintathu ngokusekelwe emazingeni ama-protein biomarker amabili futhi incoma ukuthi umuntu kufanele afune ukuqinisekiswa okwengeziwe ku-mammogram ngokushesha ngangokunokwenzeka.
13
UNowa Medical
i-lung biopsy nova
Isikhulu esiphezulu: Zhang Jian
Isungulwe: 2018
Indawo: San Carlos, California
INoah Medical iqoqe u-$150 wezigidi ngonyaka odlule ukuze isize uhlelo lwayo lwe-bronchoscopy oluqondiswa yizithombe lwe-Galaxy luqhudelane nezikhondlakhondla zemboni, inkundla ye-Intuitive Surgical's Ion kanye ne-Johnson & Johnson's Monarch.
Womathathu amathuluzi aklanywe njengophenyo oluncane olungena ngaphandle kwe-bronchi namaphaseji wamaphaphu, okusiza odokotela abahlinzayo ukucinga izilonda namaqhuqhuva okusolwa ukuthi afihle izimila ezinomdlavuza. Kodwa-ke, uNowa, njengomuntu ofike sekwephuzile, uthole imvume ye-FDA ngoMashi 2023.
NgoJanuwari walo nyaka, uhlelo lwenkampani lwe-Galaxy lwaphothula isheke lwayo lama-500.
Okuhle ngoNowa ukuthi uhlelo lusebenzisa izingxenye ezilahlwa ngokuphelele, futhi zonke izingxenye ezithinta isiguli zingalahlwa futhi esikhundleni sazo zifakwe izinto ezintsha.
14
I-Procyrion
Ukunciphisa ukwelashwa kwezifo zenhliziyo nezinso
Isikhulu Esiphezulu: U-Eric Fain, MD
Yasungulwa: 2005
Indawo: Houston
Kwabanye abantu abanesifo senhliziyo, i-feedback loop ebizwa ngokuthi i-cardiorenal syndrome, lapho imisipha yenhliziyo ebuthaka iqala ukuncipha ekhonweni layo lokususa uketshezi emzimbeni lapho imisipha yenhliziyo ebuthaka ingakwazi ukuthwala igazi nomoya-mpilo ezinso. Lokhu kunqwabelana koketshezi, nakho, kwandisa isisindo sokushaya kwenhliziyo.
I-Procyrion ihlose ukuphazamisa le mpendulo ngepompo ye-Aortix, idivayisi encane, esekelwe ku-catheter engena ku-aorta yomzimba ngesikhumba futhi yehle ngesifuba nesisu.
Ngokusebenza kufana namaphampu enhliziyo asekelwe ku-impeller, ukuyibeka phakathi komunye wemithambo emikhulu yomzimba ngesikhathi esisodwa kukhulula omunye womthwalo wenhliziyo enhla nomfula futhi kusize ukugeleza kwegazi eliya phansi ezinso.
15
I-Proprio
Dala imephu yokuhlinzwa
CEO: Gabriel Jones
Isungulwe: 2016
Indawo: Seattle
I-Paradigm, inkampani ye-Proprio, iyinkundla yokuqala yokusebenzisa ubuchwepheshe bensimu elula kanye nobuhlakani bokwenziwa ukuze kukhiqizwe izithombe zesikhathi sangempela ze-3D ze-anatomy yesiguli ngesikhathi sokuhlinzwa ukuze kusekelwe ukuhlinzwa komgogodla.
Isikhathi sokuthumela: Mar-28-2024