Incazelo yeisirinji esigcwaliswe kusengaphambili
A isirinji esigcwaliswe kusengaphambilikuyisilinganiso esisodwa somuthi lapho inaliti ibekwe khona ngumenzi. Isirinji egcwaliswe kusengaphambili iyisirinji elahlwayo enikezwa kakade igcwele into ezofakwa. Isirinji egcwaliswe kusengaphambili inezingxenye ezine ezibalulekile: i-plunger, i-stopper, i-barrel, kanye nenaliti.
Isirinji esigcwalisiwe kusengaphambiliKuthuthukisa ukusebenza kokupakisha kwe-parenteral nge-siliconization.
Ukuphathwa kwemikhiqizo yemithi ngendlela ye-parenteral kungenye yezindlela ezithandwa kakhulu ezisetshenziswa ukukhiqiza ukuqala okusheshayo kokusebenza kanye nokutholakala kwe-bioavailability okungu-100%. Inkinga enkulu eyenzeka ngokulethwa kwemithi ye-parenteral ukuntuleka kokulula, ukuthengeka, ukunemba, ukungazali, ukuphepha njll. Izithiyo ezinjalo ngalolu hlelo lokulethwa kwenza kungabi ngcono. Ngakho-ke, zonke izinkinga zalezi zinhlelo zinganqotshwa kalula ngokusebenzisa amasirinji agcwaliswe ngaphambilini.
Izinzuzo zeamasirinji agcwaliswe kusengaphambili:
1. Ukususwa kokugcwaliswa ngokweqile kwemikhiqizo yemithi ebizayo, ngaleyo ndlela kuncishiswe imfucuza.
2. Ukususwa kwamaphutha omthamo, njengoba inani eliqondile lomthamo olethwayo liqukethwe kwisirinji (ngokungafani nohlelo lwe-vial).
3. Kulula ukuthathwa ngenxa yokususwa kwezinyathelo, isibonelo, zokulungiswa kabusha, okungadingeka ohlelweni lwe-vial ngaphambi kokujova umuthi.
4. Kwengezwe ukulula kwabasebenzi bezempilo kanye nabasebenzisi bokugcina, ikakhulukazi, ukuzilawula okulula nokusebenzisa ngesikhathi sezimo eziphuthumayo. Kungonga isikhathi, futhi kusindise izimpilo ngokulandelana.
5. Amasirinji agcwaliswe kusengaphambili agcwaliswa ngemithamo enembile. Kuyasiza ekunciphiseni amaphutha ezokwelapha kanye nokungatholakali kahle.
6. Izindleko eziphansi ngenxa yokulungiselela okuncane, izinto zokwakha ezimbalwa, kanye nokugcinwa nokulahlwa okulula.
7. Isirinji esigcwaliswe kusengaphambili singahlala singahlanzeki cishe iminyaka emibili noma emithathu.
Imiyalelo yokulahlaamasirinji agcwaliswe kusengaphambili
Lahla isirinji esisetshenzisiwe esitsheni esibukhali (isitsha esivalekayo, esingabhobozi). Ukuze uphephe futhi uphile kahle wena nabanye, izinaliti nezirinji ezisetshenzisiwe akumele ziphinde zisetshenziswe.
Isikhathi sokuthunyelwe: Novemba-18-2022