Ama-Embolic Microspheres angama-microspheres e-hydrogel acindezelwayo anesimo esijwayelekile, ubuso obubushelelezi, kanye nosayizi olinganisiwe, akhiwa ngenxa yokuguqulwa kwamakhemikhali ezintweni ze-polyvinyl alcohol (PVA). Ama-Embolic Microspheres aqukethe i-macromer etholakala ku-polyvinyl alcohol (PVA), futhi ayathandeka emanzini, awakwazi ukusongelwa, futhi atholakala ngobukhulu obuhlukahlukene. Isixazululo sokugcina siyisisombululo se-sodium chloride esingu-0.9%. Okuqukethwe kwamanzi kwe-microsphere egcwele i-polymer kungu-91% ~ 94%. Ama-Microspheres angabekezelela ukucindezelwa okungu-30%.
Ama-Embolic Microspheres ahloselwe ukusetshenziselwa ukuvimbela ukukhubazeka kwemithambo yegazi (ama-AVM) kanye nezimila ezithwala igazi eliningi, okuhlanganisa ne-uterine fibroids. Ngokuvimba ukuphakelwa kwegazi endaweni okuqondiwe kuyo, isimila noma ukukhubazeka kuyaphela izakhamzimba futhi kunciphe ngobukhulu.
Kulesi sihloko, sizokukhombisa izinyathelo eziningiliziwe mayelana nendlela yokusebenzisa i-Embolic Microspheres.
Ukulungiselela izimpahla
Kudingeka ukulungiselela isirinji esingu-1 20ml, izisirinji ezimbili ze-10ml, izisirinji ezintathu ze-1ml noma ze-2ml, izikele zokuhlinzwa ezintathu, indebe ehlanzekile, imithi ye-chemotherapy, ama-embolic microspheres, i-contrast media, kanye namanzi okujova.
Isinyathelo 1: Lungiselela imithi ye-chemotherapy
Sebenzisa isikele sokuhlinzwa ukuvula ibhodlela lomuthi we-chemotherapy bese uthela umuthi we-chemotherapy enkomishini engenamagciwane.
Uhlobo kanye nomthamo wemithi yokwelapha ngamakhemikhali kuncike ezidingweni zomtholampilo.
Sebenzisa amanzi ukuze uhlanze imithi ye-chemotherapy, futhi izinga elinconywayo lingaphezu kuka-20mg/ml.
ANgemva kokuba umuthi we-chemotherapy usuncibilike ngokuphelele, isisombululo se-chemotherapy sakhishwa ngesirinji esingu-10ml.
Isinyathelo 2: Ukukhishwa kwama-embolic microspheres athwala izidakamizwa
Ama-microsphere ahlanganisiwe anyakaziswa ngokuphelele, afakwa enalitini yesirinji ukuze kulinganiswe ingcindezi ebhodleleni,bese ukhipha ikhambi kanye nama-microspheres ebhodleleni le-cillin ngesirinji esingu-20ml.
Vumela i-syringe ime imizuzu engu-2-3, futhi ngemva kokuba ama-microspheres esezinzile, i-supernatant ikhishwa esixazululweni.
Isinyathelo 3: Faka imithi ye-Chemotherapeutic ku-Embolic Microspheres
Sebenzisa izindlela ezintathu ze-stopcock ukuxhuma i-syringe ne-embolic microsphere kanye ne-syringe nomuthi we-chemotherapy, qaphela ukuxhumana ngokuqinile kanye nesiqondiso sokugeleza.
Cindezela isirinji yesidakamizwa se-chemotherapy ngesandla esisodwa, bese udonsa isirinji equkethe ama-embolic microspheres ngesinye isandla. Ekugcineni, umuthi we-chemotherapy kanye ne-microsphere kuxutshwa kwisirinji engu-20ml, shukumisa kahle isirinji, bese uyishiya imizuzu engama-30, uyishukumise njalo ngemizuzu emi-5 phakathi nesikhathi.
Isinyathelo 4: Engeza imidiya yokuqhathanisa
Ngemva kokuba ama-microsphere egcwaliswe ngemithi yokwelapha ngamakhemikhali imizuzu engama-30, kwabalwa umthamo wesisombululo.
Engeza ivolumu ye-contrast agent ephindwe ka-1-1.2 nge-stopcock enezindlela ezintathu, shukumisa kahle bese uyiyeka ime imizuzu emi-5.
Isinyathelo 5: Ama-Microsphere asetshenziswa enqubweni ye-TACE
Nge-stopcock enezindlela ezintathu, faka cishe i-1ml yama-microspheres kwisirinji esingu-1ml.
Ama-microsphere afakwe ku-microcatheter ngomjovo we-pulsed.
Ukuqondisa ukunakwa:
Sicela uqinisekise ukusebenza kwe-aseptic.
Qinisekisa ukuthi imithi yokwelapha ngamakhemikhali incibilikisiwe ngokuphelele ngaphambi kokufaka imithi.
Ukuhlushwa kwemithi ye-chemotherapy kuzothinta umphumela wokulayisha umuthi, uma ukuhlushwa kuphakeme, izinga lokumuncwa lishesha, ukuhlushwa kokulayisha umuthi okunconywayo akungaphansi kuka-20mg/ml.
Amanzi ahlanzekile kuphela okujova noma umjovo we-glucose ongu-5% okufanele asetshenziswe ukuncibilikisa imithi ye-chemotherapy.
Izinga lokuncibilika kwe-doxorubicin emanzini ahlanzekile ukuze kujovwe lalishesha kancane kunomjovo we-glucose ongu-5%.
Umjovo we-glucose ongu-5% uncibilikisa i-pirarubicin ngokushesha kancane kunamanzi ahlanzekile okujova.
Ukusetshenziswa kwe-ioformol 350 njengendlela yokuhlukanisa izinto kwakusiza kakhulu ekumisweni kwama-microspheres.
Uma kufakwa i-tumor nge-microcatheter, kusetshenziswa i-pulse injection, okuyinto ekhuthaza kakhulu ukumiswa kwe-microsphere.
Isikhathi sokuthunyelwe: Feb-28-2024